{"id":4,"date":"2021-11-26T08:39:41","date_gmt":"2021-11-26T08:39:41","guid":{"rendered":"http:\/\/lab.flygen.org\/?page_id=4"},"modified":"2026-02-09T09:08:05","modified_gmt":"2026-02-09T09:08:05","slug":"home","status":"publish","type":"page","link":"https:\/\/lab.flygen.org\/","title":{"rendered":"Hiesinger Lab"},"content":{"rendered":"\n<h4 class=\"wp-block-heading has-text-align-center\"><a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(26)00007-2\">New Paper on Retinotopic Brain Wiring in Current Biology (Feb. 2026)<\/a><\/h4>\n\n\n\n<figure class=\"wp-embed-aspect-16-9 wp-has-aspect-ratio wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Target-independent retinotopy in Drosophila \/ Curr. Biol., Feb. 3, 2026 (Vol. 36, Issue 5)\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/zhZPwjeLHVQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\"><a href=\"https:\/\/lab.flygen.org\/?p=459\">What is the Information Content of Brain Wiring?<\/a><\/h4>\n\n\n\n<h6 class=\"wp-block-heading has-text-align-center\">A new research project on the information content of brains, artificial neural networks and genomes.<\/h6>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/lab.flygen.org\/?p=459\"><img loading=\"lazy\" decoding=\"async\" width=\"785\" height=\"310\" src=\"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?fit=785%2C310&amp;ssl=1\" alt=\"\" class=\"wp-image-456\" srcset=\"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?w=785&amp;ssl=1 785w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?resize=300%2C118&amp;ssl=1 300w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?resize=768%2C303&amp;ssl=1 768w\" sizes=\"auto, (max-width: 785px) 100vw, 785px\" \/><\/a><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"wp-block-paragraph\">The information content of artificial neuronal networks can be saved in precise bits, yet no such number has ever made sense for biological neuronal networks.&nbsp; Not only the number, even what parameters should be quantified remains unclear \u2013 a true unknown unknown to be tackled experimentally within an information theoretical framework. <em><a href=\"https:\/\/lab.flygen.org\/?p=459\">Learn more here<\/a>.<\/em><\/p>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\"><a href=\"https:\/\/www.science.org\/stoken\/author-tokens\/ST-1744\/full\">Self-Organization During Visual Map Formation<\/a><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adk3043\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"309\" src=\"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/science2024-web1.jpg?resize=1024%2C309&#038;ssl=1\" alt=\"\" class=\"wp-image-399\" style=\"width:775px;height:auto\" srcset=\"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/science2024-web1.jpg?resize=1024%2C309&amp;ssl=1 1024w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/science2024-web1.jpg?resize=300%2C91&amp;ssl=1 300w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/science2024-web1.jpg?resize=768%2C232&amp;ssl=1 768w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/science2024-web1.jpg?resize=1536%2C463&amp;ssl=1 1536w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/science2024-web1.jpg?w=1551&amp;ssl=1 1551w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.science.org\/stoken\/author-tokens\/ST-1744\/full\">Agi, Reifenstein et al., &#8216;Axonal Self-Sorting without Target Guidance in Drosophila Visual Map Formation&#8217;. Science 2024.<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0960982223017372?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">Synaptic Promiscuity in Brain Development<\/a><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0960982223017372?via%3Dihub\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"541\" src=\"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/currbiol2024-webfig.jpg?resize=1024%2C541&#038;ssl=1\" alt=\"\" class=\"wp-image-401\" srcset=\"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/currbiol2024-webfig.jpg?resize=1024%2C541&amp;ssl=1 1024w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/currbiol2024-webfig.jpg?resize=300%2C158&amp;ssl=1 300w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/currbiol2024-webfig.jpg?resize=768%2C406&amp;ssl=1 768w, https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2024\/03\/currbiol2024-webfig.jpg?w=1365&amp;ssl=1 1365w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/a><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0960982223017372?via%3Dihub\">Wolterhoff and Hiesinger, Curr Biol. 2024<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>New Paper on Retinotopic Brain Wiring in Current Biology (Feb. 2026) What is the Information Content of Brain Wiring? A new research project on the information content of brains, artificial&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"nf_dc_page":"home","footnotes":""},"class_list":["post-4","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hiesinger Lab<\/title>\n<meta name=\"description\" content=\"Hiesinger Neurogenetics Laboratory - Neural Circuit Assembly.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/lab.flygen.org\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hiesinger Lab\" \/>\n<meta property=\"og:description\" content=\"Hiesinger Neurogenetics Laboratory - Neural Circuit Assembly.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/lab.flygen.org\/\" \/>\n<meta property=\"og:site_name\" content=\"Hiesinger Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-09T09:08:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?fit=785%2C310&ssl=1\" \/>\n\t<meta property=\"og:image:width\" content=\"785\" \/>\n\t<meta property=\"og:image:height\" content=\"310\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/\",\"url\":\"https:\\\/\\\/lab.flygen.org\\\/\",\"name\":\"Hiesinger Lab\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/i0.wp.com\\\/lab.flygen.org\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/vwfoundation2.jpg?fit=785%2C310&amp;ssl=1\",\"datePublished\":\"2021-11-26T08:39:41+00:00\",\"dateModified\":\"2026-02-09T09:08:05+00:00\",\"description\":\"Hiesinger Neurogenetics Laboratory - Neural Circuit Assembly.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/lab.flygen.org\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/#primaryimage\",\"url\":\"https:\\\/\\\/i0.wp.com\\\/lab.flygen.org\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/vwfoundation2.jpg?fit=785%2C310&amp;ssl=1\",\"contentUrl\":\"https:\\\/\\\/i0.wp.com\\\/lab.flygen.org\\\/wp-content\\\/uploads\\\/2025\\\/07\\\/vwfoundation2.jpg?fit=785%2C310&amp;ssl=1\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/lab.flygen.org\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Hiesinger Lab\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/lab.flygen.org\\\/#website\",\"url\":\"https:\\\/\\\/lab.flygen.org\\\/\",\"name\":\"Hiesinger Lab\",\"description\":\"How do genomes make brains?\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/lab.flygen.org\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Hiesinger Lab","description":"Hiesinger Neurogenetics Laboratory - Neural Circuit Assembly.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/lab.flygen.org\/","og_locale":"en_US","og_type":"article","og_title":"Hiesinger Lab","og_description":"Hiesinger Neurogenetics Laboratory - Neural Circuit Assembly.","og_url":"https:\/\/lab.flygen.org\/","og_site_name":"Hiesinger Lab","article_modified_time":"2026-02-09T09:08:05+00:00","og_image":[{"width":785,"height":310,"url":"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?fit=785%2C310&ssl=1","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/lab.flygen.org\/","url":"https:\/\/lab.flygen.org\/","name":"Hiesinger Lab","isPartOf":{"@id":"https:\/\/lab.flygen.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/lab.flygen.org\/#primaryimage"},"image":{"@id":"https:\/\/lab.flygen.org\/#primaryimage"},"thumbnailUrl":"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?fit=785%2C310&amp;ssl=1","datePublished":"2021-11-26T08:39:41+00:00","dateModified":"2026-02-09T09:08:05+00:00","description":"Hiesinger Neurogenetics Laboratory - Neural Circuit Assembly.","breadcrumb":{"@id":"https:\/\/lab.flygen.org\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/lab.flygen.org\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/lab.flygen.org\/#primaryimage","url":"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?fit=785%2C310&amp;ssl=1","contentUrl":"https:\/\/i0.wp.com\/lab.flygen.org\/wp-content\/uploads\/2025\/07\/vwfoundation2.jpg?fit=785%2C310&amp;ssl=1"},{"@type":"BreadcrumbList","@id":"https:\/\/lab.flygen.org\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/lab.flygen.org\/"},{"@type":"ListItem","position":2,"name":"Hiesinger Lab"}]},{"@type":"WebSite","@id":"https:\/\/lab.flygen.org\/#website","url":"https:\/\/lab.flygen.org\/","name":"Hiesinger Lab","description":"How do genomes make brains?","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/lab.flygen.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"jetpack-related-posts":[],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lab.flygen.org\/index.php?rest_route=\/wp\/v2\/pages\/4","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.flygen.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.flygen.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.flygen.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.flygen.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4"}],"version-history":[{"count":5,"href":"https:\/\/lab.flygen.org\/index.php?rest_route=\/wp\/v2\/pages\/4\/revisions"}],"predecessor-version":[{"id":572,"href":"https:\/\/lab.flygen.org\/index.php?rest_route=\/wp\/v2\/pages\/4\/revisions\/572"}],"wp:attachment":[{"href":"https:\/\/lab.flygen.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}